PUBLICACIONES (2009-2022)

 

TRABAJOS PUBLICADOS EN REVISTAS, LIBROS Y CAPÍTULOS DE LIBRO Y PRESENTACIONES A CONGRESOS DEL CIPYP (2009-2022)

 

Mode of action of the sesquiterpene lactones estafietin and eupatoriopicrin on Trypanosoma cruzi. Elso OG, Puente V, Barrera P, Sosa-Escudero MA, Sülsen VP, Lombardo ME . Phytomedicine (2022) 96: Article 153900. Aceptado en Diciembre de 2021. https://doi.org/10.1016/j.phymed.2021.153900

New antiparasitic derivatives of the furoquinoline alkaloids kokusaginine and flindersiamine” Valdez MB, Bernal Giménez DM, Fernández LR, Musikant AD, Ferri G, Saenz D, Di Venosa G, Casas A, Avigliano E, Edreira MM, Palermo J. Chem Med Chem (2022) doi: 10.1002/cmdc.202100784.

Fontana LC, Pinto JG, Vitorio GDS, Ferreira I, Pacheco-Soares C, Mamone LA, Strixino JF. Photodynamic effect of protoporphyrin IX in gliosarcoma 9l/lacZ cell line. Photodiagnosis Photodyn Ther. (2022) :102669. doi: 10.1016/j.pdpdt.2021.102669.

An increase in O-GlcNAcylation of Sp1 down-regulates the gene expression of pi class glutathione S-transferase in diabetic mice. Oliveri, L.M; Buzaleh, A.M & Gerez, E.N. (2021) Biochem Biophys. Rep https://doi.org/10.1016/j.bbrep.2021.101049 (doi: 10.1016/j.bbrep.2021.101049)

Clinical, Biochemical and Genetic characterization of ACUTE HEPATIC PORPHYRIAS in a cohort of Argentine patients. María del Carmen Martinez, Gabriela Nora Cerbino, Bárbara Xoana Granata, Batlle Alcira, Parera Victoria Estela, Maria Victoria Rossetti. Molecular Genetics and Genomic Medicine 2021;9:e1059.1-7.

Synthesis and cytotoxicity evaluation of olivacine-indole hybrids tethered by alkyl linkers” Pis Diez CM, Céspedes M, Di Venosa G, Calvo G, Avigliano E, Casas A, Palermo J. Natural Product Research (2021) doi: 10.1080/14786419.2021.1880401.

 “Apoptotic cell death induced by dendritic derivatives of aminolevulinic acid in endothelial and foam cells co-cultures”. Céspedes M, Saénz D, Calvo G, González M, MacRobert A, Battah S, Casas A, Di Venosa G. Photochemical and Photobiological Sciences (2021) doi: 10.1007/s43630-021-00025-x

“Novel meso-substituted porphyrin derivatives and its potential use in photodynamic therapy of cancer”. Vallecorsa P, Di Venosa G, Ferreyra D, Ballatore MB, Mamone L, Sáenz D, Durantini E, Casas A. BMC Cancer (2021) doi: 10.1186/s12885-021-08286-6

“Photodynamic therapy of cutaneous T-cell lymphoma cell lines mediated by 5-aminolevulinic acid and derivatives”.    Vallecorsa P, Di Venosa G, Gola G, Sáenz D, Mamone L, MacRobert A, Ramirez J, Casas A.  Journal of Photochemistry & Photobiology, B: Biology (2021) doi: 10.1016/j.jphotobiol.2021.112244

"Photosensitization of a subcutaneous tumour by the natural anthraquinone parietin and blue light" Mugas ML, Calvo G, Marioni J, Céspedes M, Martinez F, Vanzulli S, Sáenz D, Di Venosa G, Nuñez Montoya S, Casas A. Scientific Reports (2021) 11(1):23820. doi: 10.1038/s41598-021-03339-z.

Role of ABCB1 and glutathione S‑transferase gene variants in the association of porphyria cutanea tarda and human immunodeficiency virus infection. Pagnota, P; Lavandera, J.; Parera, V.; Rossetti, M.V.; Melito, V.; Zuccoli, J.R & Buzaleh, A.M. Biomed. Rep. (2020) https://doi: 10.3892/br.2020.1398. Corresponding author: Buzaleh A.M.

Acute Intermittent Porphyria in a Man with Dual Enzyme Deficiencies.  G. N. Cerbino , Abou Assali , L. S. Varela ,L. Tomassi , A. Batlle , V. E. Parera and M. V. Rossetti. Case Reports in Genetics-10/20- Pag 1-6.  Volume 2020, Article ID 8873219, 6 pages. https://doi.org/10.1155/2020/8873219

High level of haem precursors in AIP men carrying CYP2C9 1/ 2 haplotype. European Journal of molecular and clinical medicine-Lubna. Abou Assali, Diego. Miguel. Gordillo, Gabriela. Noria. Cerbino, Laura. Sabina. Varela, Victoria. Estela. Parera & Maria Victoria Rossetti1 11/2020.

Photosensitization of tumor cells mediated by parietin the natural anthraquinone parietin and blue light” Mugas ML , Calvo G , Marioni J , Céspedes M , Martinez F, Sáenz D, Di Venosa G , Cabrera JL, Nuñez Montoya S, Casas A. Journal of Photochemistry and Photobiology 214:112089 (2020) doi: 10.1016/j.jphotobiol.2020.112089.

Casas A. Clinical uses of 5-aminolaevulinic acid in photodynamic treatment and photodetection of cancer: A review. Cancer Lett. :490:165-173 (2020). doi: 10.1016/j.canlet.2020.06.008. Epub 2020 Jun 10. PMID: 32534172.

Bacterial viability after antimicrobial photodynamic therapy with Curcumin on multiresistant Staphylococcus aureus. Alves Freitas M, Correia Pereira A, Guerra Pinto J, Casas A, Ferreira-Strixino J. Fut. Microbiol. 14:739-748 (2019). doi: 10.2217/fmb-2019-0042.

Study of the relationship between variants of CYP2C9 enzyme and Acute Intermittent Porphyria manifestation. Abou Assali L, Gordillo DM, Cerbino GN, Varela LS, Batlle A ^, Parera VE, Rossetti MV.                                        Int. J. Latest Res. Sci. Technol. 8(3):1-6 (2019).

Disaccharides obtained from carrageenans as potential antitumor agents. Calvo G, Cosenza V, Sáenz D, Navarro D, Stortz C, Céspedes M, Mamone L, Casas A, Di Venosa G. Sci Rep. 9:6654 (2019). doi: 10.1038/s41598-019-43238-y.

Synthesis, 2D-QSAR studies and Biological Evaluation of Quinazoline Derivatives as potent Anti-Trypanosoma cruzi Agents. Bollini M, Bruno AM, Niño ME, Casal JJ, Sasiambarrena LD, Valdez DAG, Battini L, Puente VR, Lombardo ME. Med Chem 15:265-276 (2019) doi: 10.2174/ 1573406414666181005145042

Trypanosoma cruzi mitochondrial dysfunction and its binding to thiol groups as primary targets of the sesquiterpene lactone deoxymikanolide mode of action.  Puente V, Laurella LC, Spina RM, Lozano E, Martino VS, Sosa MA, Sülsen VP, Lombardo M.E. Phytomedicine 56:27-34 (2019).

Impacto clínico de la investigación básica: Terapia antioxidante: Un nuevo enfoque en el tratamiento de la Enfermedad de Chagas. Puente VR, Lombardo ME. La Revista del Hospital de Clínicas. Aceptado  19/04/2019. 

Synthesis and biological evaluation of new quinoline derivatives as antileishmanial and antitrypanosomal agents. Chanquia SN, Larregui F, Puente V, Labriola C, Lombardo E, García Liñares G. Bioorg Chem. 83:526-534 (2019) doi: 10.1016/j.bioorg.2018.10.053

Haplotype Analysis of Single Nucleotide Polymorphisms of CYP1A1 and CYP1A2 and its relationship with the Development of Porphyria Cutanea Tarda. Gordillo DM, Abou Assali L, Cerbino GN, Varela LS, Batlle A, Parera VW, Rossetti MV. Int J Latest Res Sci Techol 7(6):12-17 (2018).

One-step preparation of novel 1-(N-indolyl)-1,3- butadienes by base-catalysed isomerization of alkynes as an access to 5-(N-indolyl)- naphthoquinones C. Pis Diez M, Fernandez J, Di Venosa G, Casas A, Pis Diez R, Palermo J. RSC Adv. 8:35998 (2018). doi: 10.1039/C8RA05208E.

Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi.  Puente VR, Demaria AA, Frank FM, Batlle A, Lombardo ME. PLoS Negl Trop Dis (2018) 12:e0006764. doi: 10.1371/journal.pntd.0006764.

Studies of 4-arylthiazolylhydrazones derived from 1-indanones as Trypanosoma cruzi squalene epoxidase inhibitors by molecular simulations. Noguera GJ, Fabian LE, Lombardo E, Finkielsztein LM. Org Biomol Chem 16:8525-8536 (2018) doi: 10.1039/c8ob02310g.

CLCA2 epigenetic regulation by CTBP1, HDACs, ZEB1, EP300 and miR-196b-5p impacts prostate cancer cell adhesion and EMT in metabolic syndrome disease. Porretti J, Dalton GN, Massillo C, Scalise GD, Farré PL, Elble R, Gerez EN, Accialini P, Cabanillas AM, Gardner K, De Luca P, De Siervi A.  Int J Cancer. 143(4):897-906 (2018) doi: 10.1002/ijc.31379.

Effects of volatile anaesthetics on heme metabolism in a murine genetic model of Acute Intermittent Porphyria. A comparative study with other porphyrinogenic drugs. Ruspini SF, Zuccoli JR, Lavandera JV, Martínez M del C, Oliveri LM, Gerez EN, Batlle A, Buzaleh AM. Biochim. Biophys. Acta (General Subjects) (2018) doi.org/10.1016/j.bbagen.2018.02.013

Enhancement of photodynamic inactivation of Staphylococcus aureus biofilms by disruptive strategies. Gándara L, Mamone L, Bohm G, Buzzola F, Casas A. Lasers Med Sci. 32:1757-1767 (2017) doi:10.1007/s10103-017-2253-3.

Synthesis and cytotoxicity evaluation of A-ring derivatives of cycloartanone. Zambrano E, Casas A, Di Venosa G, Uriburu N, Duran F, Palermo A. Phytochem. Lett. 21:200-205 (2017) doi: 10.1016/j.phytol.2017.06.021.

Reversal of the migratory and invasive phenotype of Ras-transfected mammary cells by photodynamic therapy treatment. Calvo G, Sáenz D, Simian M, Sampayo R, Mamone L, Vallecorsa P, Batlle A, Casas A, Di Venosa G.  J. Cell Physiol. 118:464-477 (2017). doi: 10.1002/jcb.25657.

Protective effect exerted by soil phosphorus on soybean subjected to arsenic and fluoride. Bustingorri C, Noriega G, Lavado R, Balestrasse K. Redox Report. 22(6):353–360 (2017).

Sae regulator factor impairs the response to photodynamic inactivation mediated by Toluidine blue in Staphylococcus aureus. Gándara L, Mamone L, Dotto C, Buzzola F, Casas A.  Photodiagnos. Photodyn. Ther. 16:136-141 (2016). doi: 10.1016/j.pdpdt.2016.09.005.

Synthesis of chemically diverse esters of 5-aminolevulinic acid for photodynamic therapy via the multicomponent Passerini reaction. Gola G, Di Venosa G, Sáenz D, Calvo G, Cabrera G, Casas A, Ramírez J. RSC Adv. 6, 89492-89498 (2016). doi: 10.1039/c6ra15832c.

Methods for the detection of reactive oxygen species employed in the identification of plant photosensitizers. Mamone L, Di Venosa G, Saenz D, Batlle A, Casas A.  Methods 109:73-80 (2016). doi: 10.1016/j.ymeth.2016.05.020.

Photodynamic inactivation of planktonic and biofilm growing bacteria mediated by a meso-substituted porphyrin bearing four basic amino groups. Mamone L, Ferreyra D, Gándara L, Di Venosa G, Vallecorsa P, Sáenz D, Calvo G, Batlle A, Buzzola F, Durantini E, Casas A. Photochem Photobiol B Biol 161:222-229 (2016). doi: 10.1016/j.jphotobiol.2016.05.026.

Thalidomide analogues: Tumor necrosis factor-alpha inhibitors and their evaluation as anti-inflammatory agents. Casal JJ, Bollini M, Lombardo ME, Bruno AM. Eur J Pharm Sci. 83:114–119 (2016).

Mode of Action of the Sesquiterpene Lactones Psilostachyin and Psilostachyin C on Trypanosoma cruzi. Sülsen VP, Puente V, Papademetrio D, Batlle A, Martino VS, Frank FM, Lombardo ME. PLoS One 11: e0150526 (2016) doi:10.1371/journal.pone.0150526.

Metabolismo del hemo: las dos caras de los efectos de la acumulación de precursores y porfirinas Rossetti MV, Buzaleh AM, Parera VE, Fukuda H, Lombardo ME, Lavandera J, Gerez EN,  Melito VA,  Zuccoli JR, Ruspini SF, Puente VR, Diez BA,  Teijo MJ,  Cerbino GN,  Varela LS, Guolo M, Batlle A.  Acta Bioquím Clín Latinoam 50(4): 547-573 (2016).

Haplotype study in Argentinean variegate porphyria patients. Granata B, Parera VE, Batlle A, Rossetti MV. Human Heredity 80(3):139-43 (2016). doi: 10.1159/000445749.

Aminolevulinic acid dendrimers in photodynamic treatment of cancer and atheromatous disease. Rodriguez L, Vallecorsa P, Battah S, Di Venosa G, Calvo G, Mamone L, Sáenz D, Gonzalez M, Batlle A, MacRobert A, Casas A. Photochem Photobiol Sci 14:1617-1627 (2015)  doi: 10.1039/c5pp00126a.

The role of cytoskeleton and adhesion proteins in the resistance to Photodynamic Therapy. Possible therapeutic interventions. Di Venosa G,  Perotti C, Batlle A, Casas A. Photochem. Photobiol. Sci.14:1451-64 (2015) doi: 10.1039/c4pp00445k.

The Use of Dipeptide Derivatives of 5-Aminolaevulinic Acid Promotes Their Entry to Tumor Cells and Improves Tumor Selectivity of Photodynamic Therapy. Di Venosa G, Vallecorsa P, Giuntini F, Mamone L, Batlle A, Vanzuli S, Juarranz A, MacRobert A, Eggleston I, Casas A. Mol Cancer Ther. 14:440-451 (2015). doi: 10.1158/1535-7163.MCT-13-1084.

QSAR study and conformational analysis of 4-arylthiazolylhydrazones derived from 1-indanones with anti-Trypanosoma cruzi activity Noguera G.J., Fabian L.E., Lombardo E. & Finkielstein L. Eur J Pharm Sci. (2015) 78:190-197.

Acute Intermittent Porphyria in Argentina. An Update. Cerbino GN, Gerez EN, Varela LS, Melito VA,  Parera VE, Batlle A, Rossetti MV. Biomed Res Int Volume 2015, Article ID 946387 (2015) http://dx.doi.org/10.1155/2015/946387.

Experimental Protoporphyria: Effect of bile acids on liver damage induced by griseofulvin. Martinez M del C, Ruspini SF, Afonso SG, Meiss R, Buzaleh AM, Batlle, A. Biomed Res Int  (Article 436319) (2015) 1-10. http://dx.doi.org/10.1155/2015/436319.

Characterization of three Variegate Porphyria mutations using a minigene approach. Granata BX, De Conti L, Baralle M, Parera VE, Rossetti MV. J Inh Metab Dis 20:39-44 (2015) doi: 10.1007/8904_2014_388.

Photoprotective Effect of the Plant Collaea argentina against Adverse Effects Induced by Photodynamic Therapy. Mamone L, Sáenz D, Vallecorsa P, Batlle A, Casas A, Di Venosa G. Int. J. Photoenergy, Volume 2014,Article ID 436463. (2014)  doi: 10.1155/2014/436463.

The natural flavonoid silybin improves the response to Photodynamic Therapy of bladder cancer cells. Gandara L, Sandes E, Di Venosa G, Prack Mc Cormick B, Rodriguez L, Mamone L, Batlle A, Eiján A, Casas A. J. Photochem. Photobiol. B Biol. 33:55-64 (2014). doi: 10.1016/j.jphotobiol.2014.03.006.

Photosensitizing effect of Argentinean plant extracts on Gram-positive bacteria. Mamone L, Di Venosa G, Gándara L, Sáenz D, Vallecorsa P, Schickinger S, Rossetti M, Batlle A, Buzzola F, Casas AJ. Photochem. Photobiol. B Biol. 133:80-89 (2014) doi:10.1016/j.jphotobiol.2014.03.003.

Pleiotropic effects of 5-aminolevulinic acid in mice brain.  Lavandera J, Rodríguez J, Ruspini S, Meiss R, Zuccoli J, Martínez MC, Gerez E, Batlle A, Buzaleh AM. Biochem Cell Biol (2016) Doi: 10.1139/bcb-2015-0094.

Porphyria Cutanea Tarda and HFE Gene Mutations in Argentina. Colombo F, Martínez J, Varela L, Gerez E, Méndez M, Batlle A, Rossetti MV, Parera V. Br J Med Med Res 4(8):1691-1700 (2014). 

Photodynamic inactivation of Gram-positive bacteria employing natural resources. Mamone L, Di Venosa G, Gándara L, Sáenz D, Vallecorsa P, Schickinger S, Rossetti MV, Batlle A, Buzzola F, Casas A. J Photochem Photobiol B. 133:80-89 (2014).

Indole acetic acid is responsible for protection against oxidative stress caused by drought in soybean plants: The role of heme oxygenase induction. Lopez Lecube M, Noriega G, Santa Cruz D, Tomaro M. L, Batlle A., Balestrasse K. Redox Report. 19(6):242-250 (2014).

Light fractionated ALA-PDT enhances therapeutic efficacy in vitro; the influence of PpIX concentration and illumination parameters. de Bruijn H, Casas A, Di Venosa G, Gandara L, Sterenborg H, Batlle A, Robinson D. Photochem Photobiol Sci. 12:241-245 (2013). doi: 10.1039/c2pp25287b.

Protective action of antioxidants on hepatic damage induced by griseofulvin. Martinez M del C, Afonso SG, Buzaleh AM, Batlle A.TSWJ: Pharmacology Article ID 982358, 1-8 (2014) http://dx.doi.org/10.1155/ 2014/982358.

Cytochrome P450 expression in mouse brain: specific isoenzymes involved in phase I metabolizing system of porphyrinogenic agents in both microsomes and mitochondria. Lavandera J, Ruspini S, Batlle A, Buzaleh AM. Biochem Cell Biol 92:1-6 (2014) http://dx.doi.org/10.1139/bcb-2014-0088.

Trypanocidal activity of tioamide-sustituted imidazoisoquinolinones: Electrochemical properties and biological effects. Frank F, Ciccarelli A, Bollini M, Bruno A, Batlle A, Lombardo E. Evid. Based Complement. Alternat. Med. 2013:945953 (2013).

An Odd Case of Heteroallelic Acute Iintermittent Porphyria in the Argentinean Population. Piñeiro Pauwels MB, Gerez EN, Martínez MC, Melito VA, Estela Parera VE, Batlle A, Rossetti MV. Cell Mol Biol 59(Supp):OL1855-OL1860 (2013).

Heme metabolism, oxidative and nitrosative markers in a mouse model of hemochromatosis. Effect of isoflurane, ethanol and 5-aminolevulinic acid. Buzaleh AM, Moreno-Carralero MI, Méndez M, Batlle A, Enríquez de Salamanca R, Morán-Jimenez MJ. J. Pathol. Res. 2:15-20 (2013) http://dx.doi.org 10.9735/0976-8068.

Molecular analysis of the UROD gene in 17 Argentinean patients with familial porphyria cutanea tarda: Characterization of four novel mutations. Méndez M, Rossetti MV, Gómez-Abecia S, Morán-Jiménez MJ, Parera V, Batlle A, Enríquez de Salamanca A. Mol Gen Metab 105(4):629-633 (2012).

Combined chemotherapy and ALA-based photodynamic therapy in leukemic murine cells. Diez B, Ernst G, Teijo MJ, Batlle A, Hajos S, Fukuda H. Leuk Res. 36(9):1179-1184 (2012) doi: 10.1016/j.leukres.2012.04.027.

Functional associations of genetic variants involved in the clinical manifestation of erythropoietic protoporphyria in the Argentinean Population. Colombo FP, Rossetti MV, Mendez M, Martínez JE, Enriquez de Salamanca R, Batlle A, Parera VE. J Eur Eur Dermatol Venn (2012) Doi:10.1111/j.1468-3083.2012.04566.x 

Changes in actin and E-cadherin expression induced by 5-aminolevulinic acid photodinamic therapy in normal and Ras-transfected human mammary cell lines. Di Venosa G, Rodriguez L, Mammone L, Gándara L, Rossetti MV, Batlle A, Casas A. J Photochem Photobiol B: Biology 106:47-52 (2012).

Functional characterization of five protoporphyrinogen oxidase missense mutations found in Argentinean Variegate patients. Méndez M, Granata BX, Morán Jiménez MJ, Parera VE,  Batlle A,   Enríquez de Salamanca R, Rossetti MV. J Inh Metab Dis 4:91-97 (2012)  Doi 10.1007/8904.77.

Synthesis and biological evaluation of some novel 1-indanone thiazolylhydrazone derivatives as anti-Trypanosoma cruzi agents. Caputto ME, Cicarelli A, Moglione A, Moltrasio G, Lombardo E, Finkielsztein L. Eur J Med Chem 55:155-163 (2012).

Anti-parasitic effect of vitamin B12 on Trypanosoma cruzi. Antimicrob. Ciccarelli A, Frank F, Puente V, Malchiodi E, Batlle  A, Lombardo ME.  Agents Chemother. 56:5315-5320 (2012).

ALAS-1 gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FOXO1 by vanadate in diabetic mice. Oliveri LM, Davio C, Batlle A, Gerez EN. BJ Metabolism 442(2): 303-310 (2012).

Heme Oxygenase is involved in the protection exerted by jasmonic acid against cadmium stress in soybean roots. Noriega, G., Cruz, D.S., Batlle, A., Tomaro, M., Balestrasse, K. J. Plant Growth Reg 31:79-89 (2012).

The role of salicylic acid in the prevention of oxidative stress elicited by cadmium in soybean plants. Noriega G, Caggiano E, Lecube ML, Cruz DS, Batlle A, Tomaro M, Balestrasse KB. Biometals 25:1155-1165 (2012).

Identification of CYP3A5 and CYP2B6 Polymorphisms in Porphrya Cutanea Tarda associated to human Inmunodeficiency virus. Lavandera JV, Parera VE, Rossetti MV, Batlle A, Buzaleh AM. J Clin Exp Dermatol Res (2011) http://dx.doi.org/10.4172/2155-9554.S4-001.

Mechanisms of resistance to Photodynamic Therapy. Casas A. Di Venosa G, Hasan H, Batlle A. Curr Med Chem 18:2486-515 (2011). DOI: 10.2174/092986711795843272.

Cytotoxic effects of Argentinian plant extracts on tumor and normal cell lines.  Mamone L, Di Venosa G, Valla J, Rodriguez L, Gándara L, Batlle A, Heinrich M, Juarranz A, Sanz- Rodriguez F, Casas A. Cell Mol Biol (Noisy-le-grand) 57 Suppl:OL1487-99 (2011).

Mice brain nitric oxide synthase response induced by anaesthetics and other porphyrinogenic drugs  system: another target for the action of porphyrinogenic agents. Lavandera J, Batlle A, Buzaleh A.M. Drug  Metab. Lett. 5:25-29 (2011).

Identification of CYP3A5 and CYP2B6 Polymorphisms in Porphyria Cutanea Tarda Associated to Human Immunodeficiency Virus. Lavandera J, Parera V, Rossetti MV, Batlle A, Buzaleh AM. J Clin Exp Dermatol Res S:4 (2011) http://dx.doi.org/10.4172/2155-9554.S4-001

Possible involvement of stress hormones and hyperglycaemia in chronic mild stress-induced impairment of immune functions in diabetic mice. Rubinstein MR, Cremaschi GA, Oliveri LM, Gerez EN, Wald MR and Genaro AM (2010) Stress 13(5):384-391.

Heme oxygenase-1 is involved in the protection against chilling exerted by low ALA concentrations in soybean plants. Balestrasse KB, TomaroML, Batlle A, Noriega GO. Phytochemistry 71(17-18):2038-2045 (2010).

Comparison of liposomal formulations of ALA Undecanoyl ester for its use in photodynamic therapy. Di Venosa G, Hermida L, Fukuda H, Defain MV, Rodriguez L, Mamone L, MacRobert A, Casas A, Batlle A. J Photochem Photobiol B., 96:152-158 (2009). doi: 10.1016/j.jphotobiol.2009.06.001.

Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy. Rodriguez L, de Bruijn HS, Di Venosa G, Mamone L, Robinson D, Juarranz A, Batlle A, Casas A. J Photochem Photobiol B. 96:249-254 (2009). doi: 10.1016/j.jphotobiol.2009.07.001.

Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy. Casas A, Battah S, Di Venosa G, Dobbin P, Rodriguez L, Fukuda H, Batlle A, Macrobert A. J Control. Release 135:136-143 (2009). doi: 10.1016/j.jconrel.2009.01.002.

The very first description of a patient with hepatoerythropoietic porphyria in Argentina. Biochemical and molecular studies. Granata BX, Parera VE, Melito VA, Teijo MJ, Batlle AM, Rossetti MV. Cell Mol Biol 55(1):61-65 (2009)

HFE Gene mutations in patients with altered iron metabolism in Argentina. Rossetti MV, Méndez M, Afonso SG, Gerez EN, Batlle A, Muñoz A, Parera VE. Cell Mol Biol 55(2):31-35 (2009).

Novel null–allele mutations and genotype-phenotype correlation in Argentinean patients with Erythropoietic Protoporphyria. Parera VE, Koole RH, Minderman G, Rossetti MV, Batlle A, De Rooij F. Mol Med 15(11-12):425-431 (2009).

Induction of Hepatic Aminolevulinate Acid Synthetase Activity by Isoflurane in a Genetic Model for Erythropoietic Protoporphyria. Buzaleh AM, Morán-Jiménez MJ, García-Bravo M, Sampedro A, Batlle A., Enríquez de Salamanca R, Fontanellas A. Cell. Mol. Biol.  55 (1):38-44 (2009).

Glutamatergic System: another target for the action of porphyrinogenic agents. Lavandera J, Fossatti M, Azcurra J, Batlle A, Buzaleh AM. Cell Mol Biol 55 (1):23-28 (2009).

Hepatic damage and oxidative stress induced by griseofulvin in mice. Martinez M del C, Afonso SG, Meiss R, Buzaleh AM, Batlle A. Cell. Mol. Biol 55(2):121-133 (2009).

Sevoflurane: its action on heme metabolism and Phase I drug metabolizing system. Sampayo R, Lavandera J, Batlle A, Buzaleh AM. Cell Mol Biol  55(2):134-140 (2009).

Heme oxygenase contributes to alleviate salinity damage in Glycine max L. leaves. Zilli CG, Santa-Cruz DM, Yannarelli GG, Noriega GO, Tomaro  ML, Balestrasse KB. Int J Cell Biol 2009:848516 (2009) doi:10.1155/2009/848516.

Ros production by endogenously generated Protoporphyrin IX in murine leukemia cells. Diez B, Cordo Russo R, Teijo MJ, Hajos S, Batlle A, Fukuda H. Cell Mol Biol (Noisy-le-grand). 55(2):15-19 (2009).

Endogenous and exogenous porphyrins as photosensitizers in the Hep-2 human carcinoma cell line. Alvarez MG, Milanesio M, Rivarola V, Durantini E, Batlle A, Fukuda H. Cell Mol Biol (Noisy-le-grand). 55(2):8-14 (2009).

Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy. Casas A, Battah S, Di Venosa G, Dobbin P, Rodriguez L, Fukuda H, Batlle A, MacRobert AJ. J Control Release 135(2):136-143. (2009) doi: 10.1016/j.jconrel.2009.01.002.

 

 

 

 

Libros

 

Factores limitantes en la inducción de muerte celular por Terapia fotodinámicacon ALA en cultivos bi y tridimensionales de células de adenocarcinoma de pulmón Teijo MJ, Batlle A, Fukuda H. Editorial Académica Española, 2017. p. 47. ISBN 978-3-639-47221-9

Búsqueda de nuevos fotosensibilizantes y principios activos a partir de plantas regionales para su uso en el tratamiento del cáncer. Mamone L, Di Venosa G, Casas A. Editorial académica española, Berlin (2013), ISBN: 978-3-8465-7926-8.

Respuesta a la Terapia Fotodinámica empleando un láser de 635 nm. Rodriguez L, Batlle A, Casas A. Editorial académica española, 2012. p. 53. ISBN 978-3-8484-6140-0. Berlín

 

 

Capítulos de Libro

 

Study on the role of ABCB1 and glutathione S-transferase gene variants in the association of Porphyria Cutanea Tarda and human immunodeficiency virus infection. Pagnotta P, Melito V, Lavandera J, Buscalia ML, Parera VE, Rossetti MV, Zuccoli J & Buzaleh AM. New Frontiers in Medicine and Medical Research, Vol. 4, Chapter 21, pp. 149-169. Editorial: BPInternational- Ciudad: Londres (2021) DOI: 10.9734/bpi/nfmmr/v4/10963D

Diabetes and Pi Class Glutathione S-Transferase. Oliveri LM, Mora Milena S, Buzaleh AM, & Gerez EN. New Innovations in Chemistry and Biochemistry. Vol. 7, Chapter 12, pp. 135-173. Editorial: BPInternational- Ciudad: Londres (2022) DOI: 10.9734/bpi/nicb/v7/2250C.

Hepatic Damage Induced by Griseofulvin as a Murine Model of Protoporphyia. Effect of Antioxidants. Martínez M del C, Afonso SG, Batlle A & Buzaleh AM. Innovations in Science and Technology Vol. 6, Chapter 5, pp. 75-90. Editorial: BPInternational- Ciudad: Londres (2022) DOI: 10.9734/bpi/ist/v6/12456D

Mechanisms of Resistance to Photodynamic Therapy: An Update (Chapter 2). Casas A, Perotti C, Di Venosa G, Batlle A. En Resistance to Photodynamic Therapy in Cancer, Resistance to Targeted Anti-Cancer Therapeutics 5 (2015) pp 29-63, Springer International Publishing Switzerland. V. Rapozzi, G. Jori (eds.), DOI 10.1007/978-3-319-12730-9_2.

In vitro and in vivo 5-Aminolevulinic acid-based photodynamic therapy in sensitive and drug resistant leukemic murine cells. Diez B, Hajos S; Meiss R, Ernst G, Teijo MJ, Batlle A, Fukuda H, Hauppauge NY: Nova Science Publishers, 2015. p. 173-191. ISBN 978-1-63463-857-9

Studies on extracts of Argentinean plants: cytotoxic tumoral activity per se and as photosensitizers in photodynamic of cancer.  Batlle A, Mamone L, Casas A, Rodríguez L, Di Venosa G. En "In the hope of going over the present Clinical PD and PDT". A Symposium Book in "Pacifichem 2010", General Editors N. Miyoshi and Pottier, R.H., Chaper 1: (2011) pp 4 - 22. Publisher, Sankeisha Co., Ltd, Chumaru-cho, Kita-ku, Nagoya, Aichi, Japan. ISSBN978-4-88361-883-5-C3047

Drogas de abuso. Una falsa y efímera felicidad? Wolannsky M, Rossetti MV. Asociación Química Argentina (Ed, 2011. p. 347-372. ISBN 978-987-99428-3-3

Preface Batlle A, Rossetti, MV, Noisy Le Grand: CMB edition, 2009. p. 1-5.

Preface. Batlle A, Rossetti, MV. Noisy Le Grand: CMB edition, 2009. p. 1-7

 

Publicaciones en Actas de Conferencia

Durante los últimos 10 años se han publicado alrededor de 250 trabajos en Actas de Conferencias que corresponden a 43 presentaciones en Congresos Nacionales y 19 Congresos Internacionales.

 

Presentaciones a Congresos

En los últimos 10 años, en el CIPYP se han presentado trabajos en alrededor de 90 Congresos de los cuales 55 son Congresos Nacionales y 35 son Congresos Internacionales.